UNKL _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014355
Fusion event
HBV-UNKL integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1810
Orient
-
Integrated sequence
CAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCA| |GCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
End
1429136/1379135 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-3176/Upstream/608858; hsa-mir-11401/Downstream/355850;
Nearest CpG islands
chr16-CpG: 116/Target, None/Upstream, None/Downstream
Upstream sequence
GGCTGCCTCAGCCCCGGGCGTTAGGAAACCACCGGCCCCGCTGAGTCACCGCGACACAGCCCGGCTCTGCCGTGACACAGCACATTCAAGGCGCCGCGGT
Downstream sequence
CCCCCGGGGTCAGGGACACGCGAGGACAAGCTACAGACTGCTCGGAACTCAGGACAGGGCGGGGGAGCCGCCGACGCCAGGGAAATTCCCGTACCACGCG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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