Basic Information
VIS ID
TVIS10014368
Fusion event
HBV-chr17 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1830
Orient
+
Integrated sequence
ACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCAC| |CTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTG
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
End
21547428/22059136 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/2714562; hsa-mir-10226/Downstream/5234774;
Nearby gene
LINC02693(-92487) ; FAM27E5(+277942) ;
Upstream sequence
ttttcaattatatgtaatctgctgtcaaatctgtcttcaatttcaacaattatgtttttatttctggaatttctgtttggctccttctcaaatctgcctg
Downstream sequence
gtcattttttaaaatgtttttttgctttcattgagttgtattaaatttttattatatacccaacaattctaatgaagtctttattggtttgattttgctg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate