VISDB Viral Integration Site DataBase

VIS ID

TVIS10014374

Fusion event

HBV-ZNF558 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1847

Orient

+

Integrated sequence

GAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTC| |TTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTA

Chromosome

chr19

Cytoband

p13.2

Reference genome

Start

End

8931024/8820348 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-181a-5p ; hsa-mir-555 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p

Nearest miRNA

hsa-mir-1227/Upstream/430968; hsa-let-7e/Downstream/1218006;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/121904, chr19-CpG: 59/Downstream/11684

Upstream sequence

agccttccactcctagtatatgcccaagaaaatggaaagtgggcatttaaacaaaagctcgtacacaaaaattcatagtattatagcattattcttgata

Downstream sequence

gtcaaagagtggaaacaactcaaatgtttctcaatagaaaaatggattggcaaaatgtggtatgtccatacaatggaatatcattcagtcataaggaatg