VISDB Viral Integration Site DataBase

VIS ID

TVIS10014381

Fusion event

HBV-SP3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1520

Orient

-

Integrated sequence

CTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACC| |ACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCAC

Chromosome

chr2

Cytoband

q31.1

Reference genome

Start

End

174824238/173959510 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-27a-3p ; hsa-mir-223-3p ; hsa-mir-124-3p ; hsa-mir-484 ; hsa-mir-1260b ; hsa-mir-218-5p

Nearest miRNA

hsa-mir-128-1/Upstream/5376492; hsa-mir-10b/Downstream/1208123;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/603870, chr2-CpG: 54/Downstream/4092

Upstream sequence

AAGAATAAAAGGAGATTTAAAAACGTACAACCGTGACAgggccggtggctcacgcctgtaatcctagcactgtgggaggctgaggcgggcagatcacttg

Downstream sequence

aggtcaggagtttgagacccgtctgaccaacatgatgaaaccccgcctctactaaaaagacaaaaattagccgggcatggtgtacatctgtagtcccagc