VISDB Viral Integration Site DataBase

VIS ID

TVIS10014383

Fusion event

HBV-DIS3L2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2417

Orient

-

Integrated sequence

TCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCG| |TCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTT

Chromosome

chr2

Cytoband

q37.1

Reference genome

Start

End

233022801/232158091 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7a-5p ; hsa-mir-218-5p

Nearest miRNA

hsa-mir-10b/Upstream/265793; hsa-mir-149/Downstream/14562;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/195965, chr2-CpG: 174/Downstream/192879

Upstream sequence

cacatgtcttttccctagatgcccttgtcaccagtactccaatctttcttctttcaggtccctatccatctggttaaacttgtagtcactgcctatcagc

Downstream sequence

ctatcaggttgtccttcctcagctaaagtggaccacggacatagggcttgaagttctgcccactgggagaaagtttctgctatattgtcttttcagagac