VISDB Viral Integration Site DataBase

VIS ID

TVIS10014384

Fusion event

HBV-LRRTM4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1766

Orient

-

Integrated sequence

CTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGG| |TCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTT

Chromosome

chr2

Cytoband

p12

Reference genome

Start

End

77563673/77336547 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1305 ; hsa-mir-6868-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-205-5p

Nearest miRNA

hsa-mir-1285-2/Upstream/2245633; hsa-mir-10b/Downstream/2312747;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/1625534, chr2-CpG: 32/Downstream/1656519

Upstream sequence

acatagatgcaggaatcctcaacagaatactagcaaactgaatctaacagcacaccaaaaagataattcactacaattaagggggctttattcctgaaat

Downstream sequence

gcaaggatggttcaacataggcaaatcaaaaaatgtgagtcaccgtatagaattaaaagcaaaaagctatatgcttatctcagtagatggagaaaaagca