Basic Information
VIS ID
TVIS10014388
Fusion event
HBV-chr20 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1754
Orient
-
Integrated sequence
CATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGA| |TTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCA
Host Sequence
Chromosome
chr20
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
26081156/26100520 (Hg38)
End
26081156/26100520 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/7629829; hsa-mir-1-1/Downstream/107666;
Nearest TSS
ENST00000382410/Upstream/89989; ENST00000416638/Downstream/33678;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/90415, chr20-CpG: 198/Downstream/107482
Nearby gene
FAM182A(-13603) ; NCOR1P1(+2896) ;
Upstream sequence
CCACATATTATGAGATAATGAATATATTCATTATCTCAATTCATAAAACAATCATGTGATTTAGTTGGTGTTATTACTAGATTATTACCATTGtacaagt
Downstream sequence
aaagaaaataaagacaaaaaaaaaaaaagaaaagagactcagcaaaatcaaaccaataaagacttaatcagaattgttgggcatataataaaaatttaat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate