VISDB Viral Integration Site DataBase

VIS ID

TVIS10014389

Fusion event

HBV-PHF20 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2246

Orient

-

Integrated sequence

GAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGT| |TATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTT

Chromosome

chr20

Cytoband

q11.23

Reference genome

Start

End

34447417/35859495 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-197-3p ; hsa-mir-21-5p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-6802-3p ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-483-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p

Nearest miRNA

hsa-mir-103a-2/Upstream/405398; hsa-mir-1-1/Downstream/2657068;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/87167, chr20-CpG: 146/Downstream/94185

Upstream sequence

TATTACTAATTTCAGCTGTTGAGACAGCTAATTTAGCAATTTAGTAAAAGATTTTATCACTGAGGCATCATAACTTGCTACTCATCTGCTTGGATAGTAG

Downstream sequence

TTGATGTGACAATATTTGGTGATGCTATAACCTGTTGTGTCTTTGGtttttggtttttttttttttggagacagagtcttgttctgttgcctgggctggt