Fusion event
HBV-chr21 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|
Integrated sequence
GTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTC| |TTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATAT
End
18014025/16641706 (Hg38)
Nearest miRNA
hsa-let-7c/Upstream/51381; hsa-mir-155/Downstream/2044384;
Nearest cancer related gene
Upstream sequence
ttcatgctcctatgagaatctaatgccactgctgatctgacaggaggcagagctcaggcagtaatgctcactagttccgttgctcgcctcctgctgtgca
Downstream sequence
gcccagttcctaacaggacacagaccagtactggttcgcaacccagggtttgggggcccctgTCTTAGTTCCTTTGCCTTCCTTCcagatggatgcctgg
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.