Basic Information
VIS ID
TVIS10014404
Fusion event
HBV-LOC105377564 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2841
Orient
+
Integrated sequence
GACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGA| |TCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGA
Host Sequence
Chromosome
chr4
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
180892333/179971180 (Hg38)
End
180892333/179971180 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105377564
Nearest miRNA
hsa-mir-12113/Upstream/5547316; hsa-mir-1305/Downstream/2198113;
Nearest TSS
ENST00000502981/Upstream/505875; ENST00000512480/Downstream/787858;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2528626, chr4-CpG: 160/Downstream/86705
Nearby gene
LINC01098(-1980429) ; LINC00290(+1092910) ;
Upstream sequence
tctggatattagccctttgtcagatgagtagattgcaacaattttctcccattctgtgggttgcctgttcactctgatggtagtttcttttgctgtgcag
Downstream sequence
tagtggcatgtgcctgtaatcctggctgcttgagaagcagaggcaagagaatcgcttgaacccgggaggtggaggctgcagtgagccgagatcgtgccat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate