Basic Information
VIS ID
TVIS10014407
Fusion event
HBV-LOC339975 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|
Start
1863
Orient
+
Integrated sequence
AGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACT| |GTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTT
Host Sequence
Chromosome
chr4
Cytoband
q35.2
Reference genome
GRCh37/hg19
Start
188314157/187393003 (Hg38)
End
188314157/187393003 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LOC339975
Nearest miRNA
hsa-mir-12113/Upstream/2454563;
Nearest TSS
ENST00000502981/Upstream/22355; ENST00000503677/Downstream/20561;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/29755, chr4-CpG: 27/Downstream/112153
Upstream sequence
tatacatatatacgtatatatgtatttctttatatcagtgtgtttctttatatcagtgtgagaatggactaatacaCACCTATTATAATTATTTTACTTA
Downstream sequence
aagctgacaggagtttttatcaaaatctggagagatccttgtgttaggagctgctggagaggagctgtggcctcccctggactgataagtcagctggagg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate