VISDB Viral Integration Site DataBase

VIS ID

TVIS10014408

Fusion event

HBV-GABRB1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1818

Orient

+

Integrated sequence

GTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATG| |CAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTT

Chromosome

chr4

Cytoband

p12

Reference genome

Start

End

47225028/47223011 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-203a-3p ; hsa-mir-3121-3p ; hsa-mir-5582-3p ; hsa-mir-411-5p ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-4790-3p ; hsa-mir-5586-3p ; hsa-mir-100-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-5095 ; hsa-mir-7151-3p ; hsa-mir-873-3p ; hsa-mir-4329 ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-3622a-5p ; hsa-mir-4438 ; hsa-mir-4446-5p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-1224-3p ; hsa-mir-5003-3p ; hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-1251-3p ; hsa-mir-31-3p ; hsa-mir-4524b-3p ; hsa-mir-7150 ; hsa-mir-885-3p ; hsa-mir-4307 ; hsa-mir-129-5p ; hsa-mir-1271-5p ; hsa-mir-182-5p ; hsa-mir-96-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-4420 ; hsa-mir-653-3p ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-6731-3p ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-2355-3p ; hsa-mir-676-3p ; hsa-mir-4778-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-3646 ; hsa-mir-3140-5p ; hsa-mir-1910-3p ; hsa-mir-2682-5p ; hsa-mir-34b-5p ; hsa-mir-4423-3p ; hsa-mir-449c-5p ; hsa-mir-6511a-5p ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-8068 ; hsa-mir-940

Nearest miRNA

hsa-mir-12113/Upstream/6720892; hsa-mir-1243/Downstream/429658;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/190088, chr4-CpG: 21/Downstream/202664

Upstream sequence

ATTCAACCTCTGGCTTTATGCAAAAATTTAAAACATTTTCATTTGTGTCTTCCTTTTCATGTAATGCGAAGTACCTCACTTAGTCATGCTCTGTGTTTGC

Downstream sequence

CATTGTAGTACCCCAGGTTCTTCATAGTCCAGCAAAGGAGGAGCAATATCCCTAAGGCAATAATACCACCTACCGGGAACATTTCTGTAGCAAAGATAAC