VISDB Viral Integration Site DataBase

VIS ID

TVIS10014421

Fusion event

HBV-PCLO integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1841

Orient

+

Integrated sequence

TTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAAT| |CATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTG

Chromosome

chr7

Cytoband

q21.11

Reference genome

Start

End

82559836/82930520 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-136-5p ; hsa-mir-127-5p ; hsa-mir-432-5p ; hsa-mir-3166 ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-548e-5p

Nearest miRNA

hsa-mir-10525/Upstream/7015251; hsa-mir-10399/Downstream/9273495;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/486316, chr7-CpG: 81/Downstream/231838

Upstream sequence

CAGAGGGAGGAAAGTGAGTTTGTGTTAAATCATATACTTTATGGATGTGTCTGTGCTTGCTACTCCAGGCAGGAGGTAAATGAATAAACAGAATAACAAT

Downstream sequence

ATTATCCAAGAGGTAAATGTTAGCATAACACAAAAATACTCAATTCATTTCTACAAAAGTAGAAACTAATGTTCAAAGAGGTTATAATAGAATGCATGAA