VISDB Viral Integration Site DataBase

VIS ID

TVIS10014424

Fusion event

HBV-NRG1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1753

Orient

-

Integrated sequence

ACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAG| |ATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTC

Chromosome

chr8

Cytoband

p12

Reference genome

Start

End

32283953/32426437 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-125a-3p

Nearest miRNA

hsa-mir-124-1/Upstream/2469089; hsa-mir-10400/Downstream/8844611;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/785607, chr8-CpG: 169/Downstream/121452

Upstream sequence

aaattacctccccccgggttcctcttgtgaaacttgggaattgtggaagttgtaattaaaaatgagattcaggggggacacagccaaaccatatcagtgt

Downstream sequence

TTCATAAACAATTCCTTGTGTTTTAGTTTACAGTATGTCCAGAATATAGGACTTGCCTACTGTAATGTATAAAACAAAAGAACTTCAGGTTGATTTATTT