VISDB Viral Integration Site DataBase

VIS ID

TVIS10014437

Fusion event

HBV-CORO2A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1783

Orient

-

Integrated sequence

GTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGC| |TGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTG

Chromosome

chr9

Cytoband

q22.33

Reference genome

Start

End

100940295/98178013 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-21-5p ; hsa-mir-6778-3p ; hsa-mir-6128 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-3691-3p ; hsa-mir-4279 ; hsa-mir-8081 ; hsa-mir-1231 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-516b-5p ; hsa-mir-7977 ; hsa-mir-3120-5p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-4267 ; hsa-mir-6736-3p ; hsa-mir-5588-3p ; hsa-mir-29b-2-5p ; hsa-mir-3187-3p ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-4755-3p ; hsa-mir-29b-1-5p ; hsa-mir-4507 ; hsa-mir-3940-5p

Nearest miRNA

hsa-let-7a-1/Upstream/814332; hsa-mir-12126/Downstream/51136;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/58635, chr9-CpG: 24/Downstream/13991

Upstream sequence

tcccgtttccaacgaaatcctcaaagctatccaaatatccacttgcagattctacaaaaagagtgtttcaaaactgctctatcaaaagaaaggttcaact

Downstream sequence

ctctcactttttttcttttttaaatttatttttattaaaaacatttttttagagacagagtctcgctctgtcgcctaggctggagtgcagtggtgccatc