KIRREL3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014442
Fusion event
HBV-KIRREL3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|
Start
1883
Orient
+
Integrated sequence
TGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTG| |CCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTA
Host Sequence
Chromosome
chr11
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
126793007/126923111 (Hg38)
End
126793007/126923111 (Hg38)
Orient
+
Location type
Intronic
Target gene
KIRREL3
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-let-7a-2/Upstream/3541599; hsa-mir-3167/Downstream/65347;
Nearest TSS
ENST00000527297/Upstream/267025; ENST00000532988/Downstream/17548;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/506136, chr11-CpG: 27/Downstream/77219
Upstream sequence
ggctcccatggcagcatgccctcctggttttcctcctccttctctggatgtttctgctcagcttgccttgtggatcttcttcttcttcttctccttctcc
Downstream sequence
ttctccttctccttcttctcttcttcttcttcttcttcttcttcttcttcttcttcttcttcttctcttcttcttctcttcttcttcttcttcttcttct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate