VISDB Viral Integration Site DataBase

VIS ID

TVIS10014443

Fusion event

HBV-LARP4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

743

Orient

+

Integrated sequence

GGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATG| |GATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTA

Chromosome

chr12

Cytoband

q13.12

Reference genome

Start

End

50794252/50400469 (Hg38)

Orient

-

Location type

upstream

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-mir-423-3p ; hsa-mir-148b-3p

Nearest miRNA

hsa-mir-1244-3/Upstream/166257; hsa-let-7i/Downstream/2498420;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/116714, chr12-CpG: 31/Downstream/297

Upstream sequence

attgttttaagatcaattaacataaaatgcttagtatagtgccaaacacaatgtaagcatttaatatacattagctgctattAACATATTTGCTAGTATC

Downstream sequence

ATAGTTTTTTGTTTTTTTTTTCTTGTCTACTTTTCTTCTGTGAGCCACCACTTTTCGGCAGGGTTGGTTTGTTCAGTACACTTCGCCAAGGTCGGCTTTA