VISDB Viral Integration Site DataBase

VIS ID

TVIS10014457

Fusion event

HBV-chr1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2052

Orient

-

Integrated sequence

GTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCT| |CACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACC

Chromosome

chr1

Cytoband

q23.3

Reference genome

Start

End

161093484/161123694 (Hg38)

Orient

-

Location type

Intronic

Target gene

DEDD ; NIT1

miRNAs that regulate target gene

hsa-mir-224-5p ; hsa-mir-24-3p ; hsa-mir-935 ; hsa-mir-615-3p ; hsa-let-7b-5p

Nearest miRNA

hsa-mir-101-1/Upstream/1223615; hsa-mir-1182/Downstream/103492;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/5372, chr1-CpG: 52/Downstream/35654

Upstream sequence

cactgcactccagcctgggcgacagagggagactctgtctcaaaaaaaaaaaaaaaaaagacaaGACATGTGAGAGCAAATACAGGACCTAGGAGAAATG

Downstream sequence

TCACCTCGCCTGATTTTTTTTTTTTATGGGGCAAGATGTGGGCGCACAGCATCCTTTCATTTAAGCTGGCAAAGCCCAGAATGTGATGGGATCAGTGTCC