Basic Information
VIS ID
TVIS10014462
Fusion event
HBV-LINC01347 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|Polymerase|
Start
1543
Orient
+
Integrated sequence
TGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGC| |GGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGC
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
243225554/243062252 (Hg38)
End
243225554/243062252 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01347
Nearest miRNA
hsa-mir-101-1/Upstream/1929906; hsa-mir-3124/Downstream/283924;
Nearest TSS
ENST00000473358/Upstream/54784; ENST00000439562/Downstream/64446;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/171482, chr1-CpG: 34/Downstream/39386
Upstream sequence
cctcccgcagtttccatctgagtcagagtaaaagccaaagccccagcaataacctcccagggcttatgtgatctgtactgatccccacccagcaactccc
Downstream sequence
tggctccctcccctaattctctccctctctccgtctgctccatgggcctccttccagagcctcagacacacctcagacactttattctattgtttctgcc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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