VISDB Viral Integration Site DataBase

VIS ID

TVIS10014467

Fusion event

HBV-ADARB2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1377

Orient

+

Integrated sequence

GAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCAT| |GGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTT

Chromosome

chr10

Cytoband

p15.3

Reference genome

Start

End

1292785/1250733 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-4420 ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p ; hsa-mir-144-5p ; hsa-mir-4795-5p ; hsa-mir-34c-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-4295 ; hsa-mir-301a-3p ; hsa-mir-3666 ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-3117-5p ; hsa-mir-6776-3p ; hsa-mir-4753-5p ; hsa-mir-6768-3p ; hsa-mir-497-3p ; hsa-mir-2681-5p

Nearest miRNA

hsa-mir-5699/Upstream/608955; hsa-mir-107/Downstream/825286;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/8374, chr10-CpG: 74/Downstream/75975

Upstream sequence

tacccttaaacttcccagcctgcagaagcatgagctagataaaccactattttttataaagtacccagtctgatgtattctgttatagcaacacaaaatg

Downstream sequence

aactaagatagttatttgtttttaactgggcaagctgattctaaaaggaaacccagaaaattctgaaaaagaaggctaatgctggagacaagccctagtg