VISDB Viral Integration Site DataBase

VIS ID

TVIS10014472

Fusion event

HBV-TLL2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

525

Orient

+

Integrated sequence

CCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACC| |TGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGG

Chromosome

chr10

Cytoband

q24.1

Reference genome

Start

End

98178692/96418935 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-944 ; hsa-mir-4803 ; hsa-mir-548c-3p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-2277-3p

Nearest miRNA

hsa-mir-107/Upstream/354536; hsa-mir-1287/Downstream/409734;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/34179, chr10-CpG: 150/Downstream/93515

Upstream sequence

aattaatatgaatatataaattaataattattaatagataaattaaaaagcaaTATGAAGAGTTATGGCAGCTACAGAAACAAGACCCAAGGAAAAAGCT

Downstream sequence

TCTCCCTTGGGCCAACTTGACATAGATTCCCTGACAAAATTGATACTTGGTCTCTAGTAGCAGCCTGTAACTCCTGGATGATGGGGTGGGCCTTTGGCTA