Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014484
Fusion event
HBV-EEF1DP3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
727
Orient
+
Integrated sequence
TTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTT| |GGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGT
Host Sequence
Chromosome
chr13
Cytoband
q13.1
Reference genome
Start
End
32433890/31859753 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-mir-2276/Upstream/7697249; hsa-mir-1267/Downstream/7804281;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/12616, chr13-CpG: 33/Downstream/92992
Upstream sequence
TCTGACCACGTTCTCTCTGTCTTTGCTTTATAAGTGGTTTATTCCTCAGAGGTAGCGGTGATTCAGGCCCCGGAGGACCGCTCCAGCCTATTTGAATAAA
Downstream sequence
CTATCAATAACATTAAAAGCCTTCGCAGACACTGATGTTTGCCAGCACTTACAGGCTAGTGCAAATTGGATGAGTGCCTTGTTGGTGTTTTCAGTTCCTC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.