Fusion event
HBV-SYNE3 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|
Integrated sequence
CTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGT| |GTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGA
End
95877873/95411536 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1260a/Upstream/273550; hsa-mir-1185-1/Downstream/4697883;
Upstream sequence
CAGTAGCTTGGAGTAGTTTTGAGGACTGTGAGGTCCATTGGGTCAGAGAGTGGGGAGTGGGAAAGGTTGGTGATCAACTATTTTGATGTCTGTCTTGGAA
Downstream sequence
GCAGCAAGGGCTGTAGTTGCCCACACCTCCCTCCAATGCTGACCTAGACTGGTGACAATGAGATTGGGGTGAGAATTAGCTGAGTGCCCATGAGAGAGGG
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.