Fusion event
HBV-chr16 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
CAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTA| |TTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGA
End
79659226/79625329 (Hg38)
Nearest miRNA
hsa-mir-1225/Upstream/2756310; hsa-mir-11401/Downstream/1759689;
Nearest cancer related gene
Upstream sequence
GTGGGGAAGGAATCACAGGGTttattattattattattattattattTTTTAATGTCTAAACTCATTTTGTCTTTGCAACATCAAAACACTGTTGGCAAT
Downstream sequence
TTCCTTTACAACTCATGGCTAATTTACAGAAGGGATTTTTATGAAAATGTTTTCCTTCATTCCCATGGATGGTGATGCTACCTGGGGGGCAGGTACTCAG
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.