VISDB Viral Integration Site DataBase

VIS ID

TVIS10014501

Fusion event

HBV-MBTD1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1509

Orient

+

Integrated sequence

CGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGT| |TCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGC

Chromosome

chr17

Cytoband

q21.33

Reference genome

Start

End

49262480/51185119 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-151a-3p ; hsa-mir-128-3p ; hsa-mir-101-3p ; hsa-mir-27a-3p ; hsa-mir-149-5p ; hsa-mir-1277-5p ; hsa-mir-7856-5p ; hsa-mir-6083 ; hsa-mir-3658 ; hsa-mir-190a-3p ; hsa-mir-3688-3p ; hsa-mir-8076 ; hsa-mir-5011-5p ; hsa-mir-590-3p ; hsa-mir-5587-5p ; hsa-mir-676-5p ; hsa-mir-6507-3p

Nearest miRNA

hsa-mir-10226/Upstream/416389; hsa-mir-1250/Downstream/5706151;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/17833, chr17-CpG: 150/Downstream/74622

Upstream sequence

TATGAGGGAGGCAAAAGCTAAAGAACATATCCTAAAATGGCAAAAACCACCAAAAAACCAACAACGGAAACAAACAAGAAAACCCCCATAGGTGCAAAAA

Downstream sequence

TATTAGCAAACAGAAGAATGAGAAGAAAACAGAGCTAGGTAACAAGTCTCATCTAGGTTTTCAACATACAAGACATTTTAAAGAATGCTCATTACAGAAA