Basic Information
VIS ID
TVIS10014505
Fusion event
HBV-LOC112268189 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1198
Orient
+
Integrated sequence
TCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAAC| |CCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTT
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
79435706/81468680 (Hg38)
End
79435706/81468680 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC112268189
Nearest miRNA
hsa-mir-10226/Upstream/17492; hsa-mir-4525/Downstream/225077;
Nearest TSS
ENST00000595228/Upstream/6121; ENST00000430912/Downstream/12890;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/4569, chr17-CpG: 91/Downstream/12512
Nearby gene
BAHCC1(-2348) ; ACTG1(+41291) ;
Upstream sequence
GGCAGGGCGTTGTGGGAAGGACAGTCAGTGGGGCTGGGCATGCACAGCTGCGGAGCCCCAAGGGTTAAACATGCAAGACTACACTTTGATCAAGACAAAC
Downstream sequence
GGGCCATTATGTGAAATGCTGGAGCAAGATGAATGCTGGCGCTGGGTGAGTGAGATCAATAAAAGTGATGTTTTATCAGGTAGAAATGACAACCTGGCTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate