VISDB Viral Integration Site DataBase

VIS ID

TVIS10014507

Fusion event

HBV-NOL4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1840

Orient

+

Integrated sequence

GTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAA| |TCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGT

Chromosome

chr18

Cytoband

q12.1

Reference genome

Start

End

31590101/34010137 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-181a-5p ; hsa-mir-4776-3p ; hsa-mir-3972 ; hsa-mir-5006-5p ; hsa-mir-4755-3p ; hsa-mir-1202 ; hsa-mir-129-5p

Nearest miRNA

hsa-mir-1-2/Upstream/3711177; hsa-mir-122/Downstream/1581600;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/431114, chr18-CpG: 45/Downstream/148946

Upstream sequence

CTTGTCATCTGAGTTATCCTCTTGACCCCAGCTAACCCTAAGATCGCCATTTTAAAAGTATTAAAAAGCATACCATATTtttgtacctattaaccatcta

Downstream sequence

cacttcccccctctccccattactcttctcaccctctggtaaccatcattctacactatatctccatgatttcaaatgttttaatttttggcttccacgt