VISDB Viral Integration Site DataBase

VIS ID

TVIS10014513

Fusion event

HBV-POU2F2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1405

Orient

+

Integrated sequence

GCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGAT| |CCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTG

Chromosome

chr19

Cytoband

q13.2

Reference genome

Start

End

42675971/42171819 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-9-5p ; hsa-mir-4768-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-4307 ; hsa-mir-5011-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-6832-3p ; hsa-mir-410-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-6755-5p ; hsa-mir-6841-5p ; hsa-mir-6512-5p ; hsa-mir-6768-3p ; hsa-mir-6888-3p ; hsa-mir-6794-3p ; hsa-mir-3120-5p ; hsa-mir-1304-3p ; hsa-mir-3162-3p ; hsa-mir-4639-3p ; hsa-mir-510-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-504-5p ; hsa-mir-6839-3p ; hsa-mir-659-3p ; hsa-mir-29b-2-5p ; hsa-mir-4753-3p ; hsa-mir-130b-5p ; hsa-mir-218-5p ; hsa-mir-129-5p ; hsa-mir-133a-3p ; hsa-mir-133b ; hsa-mir-3124-3p ; hsa-mir-323b-5p ; hsa-mir-410-5p ; hsa-mir-494-5p ; hsa-mir-6843-3p ; hsa-mir-6848-3p ; hsa-mir-92a-1-5p

Nearest miRNA

hsa-mir-10395/Upstream/38306; hsa-let-7e/Downstream/179312;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/38287, chr19-CpG: 32/Downstream/5333

Nearby gene

LOC100505622(-34720) ; DEDD2(+26774) ;

Upstream sequence

GGGGAGGGTCCCCAGTCTGCTCTTATACTTGCGTGTGTGGGCCACAGCCCTATACTTTATAGGATCCTGAGAGTGTGGACTAAAGTAACCCCCAACCTTG

Downstream sequence

TTGGTTTCTGTGAGGGAGACCCTGAATGGATGCCAGAATAAAGGTCCCTGTGTGTGTGTGCACAAGCACACTCATGCTCATAGACAAGTCCGTATTGTCC