Basic Information
VIS ID
TVIS10014523
Fusion event
HBV-LOC101929418 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|Polymerase|
Start
1398
Orient
+
Integrated sequence
GCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCA| |ACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCT
Host Sequence
Chromosome
chr2
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
30308399/30085533 (Hg38)
End
30308399/30085533 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC101929418
Nearest miRNA
hsa-mir-1301/Upstream/2089084; hsa-mir-10b/Downstream/2446620;
Nearest TSS
ENST00000437798/Upstream/163967; ENST00000482474/Downstream/50800;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/163849, chr2-CpG: 170/Downstream/60912
Nearby gene
ALK(-163922) ; YPEL5(+61351) ;
Upstream sequence
GAGGAGAAGCTGCTCTTGTTCACATTCTGCCCATTTAACACATTCATCCAGGCTCCAGGCATTTCCTACAGGAGAAAATCTCAGCTCCATCCTCTCAAAG
Downstream sequence
AACAATGCAGAGACAATTACTGAATGCTGAGGAAAGATACTTCATTTGCAATCGGGCATCAGGCAGGGAAGTGGGGCTTTCAAGAATGCCTGTGATTCCA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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