VISDB Viral Integration Site DataBase

VIS ID

TVIS10014535

Fusion event

HBV-ABCC5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2095

Orient

-

Integrated sequence

GATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAAC| |TAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAG

Chromosome

chr3

Cytoband

q27.1

Reference genome

Start

End

183716422/183998634 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-1229-3p ; hsa-mir-935 ; hsa-mir-423-5p ; hsa-mir-188-5p ; hsa-mir-129-5p ; hsa-mir-4308 ; hsa-mir-4254 ; hsa-mir-6510-5p ; hsa-mir-1304-5p ; hsa-mir-1273h-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-4771 ; hsa-mir-3166 ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-3184-5p ; hsa-mir-873-3p ; hsa-mir-499b-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-491-5p ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-185-3p ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-1199-3p ; hsa-mir-2467-3p ; hsa-mir-6820-5p ; hsa-mir-6087 ; hsa-mir-6805-5p ; hsa-mir-4758-3p ; hsa-mir-766-3p ; hsa-mir-610 ; hsa-mir-1224-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-4323 ; hsa-mir-634

Nearest miRNA

hsa-let-7g/Upstream/111749; hsa-mir-1224/Downstream/242771;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/113548, chr3-CpG: 86/Downstream/18718

Upstream sequence

tagatatttctttttcaccataggccccaaatggctctgaaatatccatttacagattgtagaaaaagactgtttccaagctgctcaatcaaaagaaagt

Downstream sequence

TGAGCTAAGGGTCTTGATCACTATGCTATGGGCCTGTCaaaaaaaacaaaaaaacaaaaaacaaaaccaagcaaataaaccataactgtacaaaaTGATC