Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014545
Fusion event
HBV-STK32B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
744
Orient
+
Integrated sequence
GGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGG| |ATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAA
Host Sequence
Chromosome
chr4
Cytoband
p16.2
Reference genome
Start
End
5306907/5305180 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-4800/Upstream/3055024; hsa-mir-12113/Downstream/618095;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/253023, chr4-CpG: 18/Downstream/263228
Upstream sequence
CAGAATGAGGAAAAAAATAAATATAGATAGACAGATATAGATGTTTGTACCAAAACAAGTTGATTATTCTCTTTAGATTTGGATATAGATAATGCCCTGA
Downstream sequence
attagggtgatactggcttcatagaatgttttggggaagattgcctctttctttatcttttggaatagtgtctcagtaggattggtcccaattcttcttt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.