Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014551
Fusion event
HBV-CDH18 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1845
Orient
+
Integrated sequence
GGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATC| |TCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGT
Host Sequence
Chromosome
chr5
Cytoband
p14.3
Reference genome
Start
End
19554758/19554649 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10397/Upstream/2398657; hsa-mir-103a-1/Downstream/12381453;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1899035, chr5-CpG: 45/Downstream/750804
Upstream sequence
tataaatatttatgttttatagaaaaaaaaactagtgcatttgatcctgaaacattgctccagacccttttggagacattgagtaatatagaatatatga
Downstream sequence
CTAGGGCTAAGGTACTTATTCTAATTATGCACACCTTCCCAGAACACAGGTTCCCTTCCTGGGGCTAAGCCTGGTTTGGTCACAAGATGGTGACATTAGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.