VISDB Viral Integration Site DataBase

VIS ID

TVIS10014557

Fusion event

HBV-EYS integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1379

Orient

+

Integrated sequence

ACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGG| |CTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGG

Chromosome

chr6

Cytoband

q12

Reference genome

Start

End

66056070/65346177 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-510-3p ; hsa-mir-376a-5p ; hsa-mir-4680-5p ; hsa-mir-494-3p

Nearest miRNA

hsa-mir-10398/Upstream/7955965; hsa-mir-10524/Downstream/6030783;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/44589, chr6-CpG: 34/Downstream/441605

Upstream sequence

AGGGCCGGCATTAGGGGGAGGAAGGCAGATGAGAGGAGAGGAAGCTATACCAGTAACTTTTTAAACGAATGGCAAAAAGACCTTTTCTATTTTAGATTTC

Downstream sequence

agtcatcatggcccatccttgtatggtcagtttccagtcagccttcttagttcctctccgttaaatatgatcaccccacatttggcagaaagactccaaa