VISDB Viral Integration Site DataBase

VIS ID

TVIS10014564

Fusion event

HBV-LONRF1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

973

Orient

+

Integrated sequence

ATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCC| |TATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGT

Chromosome

chr8

Cytoband

p23.1

Reference genome

Start

End

12589471/12731962 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-769-5p ; hsa-mir-335-5p ; hsa-mir-128-3p ; hsa-mir-19b-3p ; hsa-mir-1226-3p ; hsa-mir-301a-3p ; hsa-mir-27a-3p ; hsa-mir-216a-3p ; hsa-mir-27b-3p ; hsa-mir-513a-5p ; hsa-mir-506-5p ; hsa-mir-4328 ; hsa-mir-3681-3p ; hsa-mir-574-5p ; hsa-mir-19a-3p ; hsa-mir-8055 ; hsa-mir-5096 ; hsa-mir-8081 ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-4758-5p ; hsa-mir-1238-5p ; hsa-mir-5585-3p ; hsa-mir-2052 ; hsa-mir-3659 ; hsa-mir-3148 ; hsa-mir-1252-5p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-651-3p ; hsa-mir-561-3p ; hsa-mir-3117-3p ; hsa-mir-7162-3p ; hsa-mir-4649-3p ; hsa-mir-1-5p ; hsa-mir-3200-5p ; hsa-mir-1197 ; hsa-mir-7110-3p ; hsa-mir-342-3p ; hsa-mir-4639-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p

Nearest miRNA

hsa-mir-124-1/Upstream/4658; hsa-mir-10400/Downstream/2121476;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/66245, chr8-CpG: 223/Downstream/22091

Upstream sequence

agaatatgatgagtgaaaataaatacatacaatatgagtgtgtagaccgattgtatccattttaagaaagacaagagccaaggtaatttaccaaatacct

Downstream sequence

TCAATTCTGGATTAATTAGTGAGGGGAACATTACAATGGATGATGCTAAGCAAAAAAACCTGTCTGAGGCTTTGCACAAGAGCAGTAAAGATAGTTGGCT