VISDB Viral Integration Site DataBase

VIS ID

TVIS10014566

Fusion event

HBV-MTMR7 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

640

Orient

+

Integrated sequence

CAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCC| |TATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTAT

Chromosome

chr8

Cytoband

p22

Reference genome

Start

End

17164019/17306510 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-3977 ; hsa-mir-103a-2-5p ; hsa-mir-665 ; hsa-mir-4768-3p ; hsa-mir-409-3p

Nearest miRNA

hsa-mir-124-1/Upstream/2453000; hsa-mir-10400/Downstream/375068;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/59156, chr8-CpG: 64/Downstream/106584

Upstream sequence

TTATTGCATGTAATTGTTAAGTAAGGTACAAGCACAGAAATCAACTGCTATTCAAGGAATTATAAAGTAACTTTATAAGCCTTATATAAATAAGCCTAGT

Downstream sequence

TCCCATTGCTTTGCTTTTCAAGAGCACATCAGACTCGTCTTCCTCAAATTTGTATTGATTTTAAAATGAAGACTCCTTAGCCCTTTACACTACTGTGTGA