Basic Information
VIS ID
TVIS10014569
Fusion event
HBV-chr8 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
3123
Orient
+
Integrated sequence
CCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAGTCAGGAA| |GGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG
Host Sequence
Chromosome
chr8
Cytoband
q11.23
Reference genome
End
54296593/53384033 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/10487758; hsa-mir-10400/Downstream/8330755;
Nearby gene
OPRK1(-132399) ; ATP6V1H(+331510) ;
Upstream sequence
aggttgggcgaggtggctcacgcctgtaatcccagcactttgggaggccaatgcaggcagatcacttgaggtcaggagtttgagatcagcctggccaaca
Downstream sequence
ggaggaataagccttagtgatctattgcacagaacgatgactataacaaataatgatgtattagatacttcaaaattgctaagagagtagattttaaatg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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