Fusion event
HBV-KLF4 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG
End
110252240/107489959 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7a-1/Upstream/888937; hsa-mir-12126/Downstream/1556270;
Nearest cancer related gene
Upstream sequence
TTGGCTGCAGGTTATCTGCGGACATCCCTGTTTGCACATCACGGGAGTCTAGATTGTAAGACCCCTCCTCATACTCTAAAACTTCCTCTGGTTCCTCGGT
Downstream sequence
ggctgggccgggcCGTGACGCCAGCCAGGCAGCTGGCGGGCTGGAGCCGAGCTGACGCcggcggcagtggtgtcggcggcggcggcggcgTCCGCCCCAG
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.