VISDB Viral Integration Site DataBase

VIS ID

TVIS10014583

Fusion event

HBV-LMNA integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|middle S protein|

Start

72

Orient

-

Integrated sequence

AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCC| |AGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACAT

Chromosome

chr1

Cytoband

q22

Reference genome

Start

End

156057356/156087565 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-340-5p ; hsa-mir-9-5p ; hsa-mir-124-3p ; hsa-mir-296-3p ; hsa-mir-615-3p ; hsa-let-7e-5p ; hsa-let-7a-5p ; hsa-mir-205-5p

Nearest miRNA

hsa-mir-101-1/Upstream/136229; hsa-mir-1182/Downstream/332776;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/4766, chr1-CpG: 20/Downstream/18895

Nearby gene

MEX3A(-5567) ;

Upstream sequence

ctcctgaccttgtgatccacccacctcagcctcccaaagtgctggaattacagtcgtgagccatcgcgcccggcTCCCAttttcttttcttttcttttct

Downstream sequence

ttttttgagacaaggtcttgctctgtcacccagactggaatgcagtggcttgatcatggctcactgaagccttgatctcccaggataaagtgatcctccc