VISDB Viral Integration Site DataBase

VIS ID

TVIS10014591

Fusion event

HBV-UNC80 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2392

Orient

-

Integrated sequence

GCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTC| |GCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGC

Chromosome

chr2

Cytoband

q34

Reference genome

Start

End

210787051/209922327 (Hg38)

Orient

+

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-4687-3p ; hsa-mir-7974 ; hsa-mir-4999-5p ; hsa-mir-4742-3p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-889-5p ; hsa-mir-888-5p

Nearest miRNA

hsa-mir-10b/Upstream/2167446; hsa-mir-1244-1/Downstream/2503936;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/112802, chr2-CpG: 48/Downstream/80121

Upstream sequence

CACATTCCCCATTTTGTTTGCCAGTAGAAGAAGTCACCAATCTGGCATCCCGTCGACTGTCTGTGAGTCCATCCTGCACCTCCAGCACTTCCCACAGGAA

Downstream sequence

TTATTCCTTCCGCCGCGGGTCAGTCTGGTCAGTGCGTTCAGCCGTCAGTGCTGAAGGTGTGTCCTCTTGCATACGTTTTATTTCTCCTGACTTATGTGTT