ADAMTS19 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014595
Fusion event
HBV-ADAMTS19 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1250
Orient
-
Integrated sequence
CGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTT| |TCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCC
Host Sequence
Chromosome
chr5
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
128836155/129500462 (Hg38)
End
128836155/129500462 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADAMTS19
Nearest miRNA
hsa-mir-10397/Upstream/103315; hsa-mir-103a-1/Downstream/2717387;
Nearest TSS
ENST00000502646/Upstream/38786; ENST00000509467/Downstream/187638;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/38738, chr5-CpG: 205/Downstream/403398
Upstream sequence
CTTTATTTATGGAGCTAGCATTTGAACAGGCCTCGCACCCTCCCTGGGCTGTCACGCTCGCTGGAGGTTAGCCTCGTCTTGTAAATACTTAGGATTACAG
Downstream sequence
ctcagtctctggggatctcagtcttttcctgtgaggatggtgaattcatcttctcaggtagtcacttgcaacgcctgccttagtctttgggtatctgttg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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