VISDB Viral Integration Site DataBase

VIS ID

TVIS10014596

Fusion event

HBV-CDH12 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1369

Orient

+

Integrated sequence

ATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATC| |GTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGG

Chromosome

chr5

Cytoband

p14.3

Reference genome

Start

End

22667211/22667102 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-4455 ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-8068 ; hsa-mir-6867-5p ; hsa-mir-574-5p ; hsa-mir-759 ; hsa-mir-4433a-5p ; hsa-mir-4433b-5p ; hsa-mir-4646-3p

Nearest miRNA

hsa-mir-10397/Upstream/5511110; hsa-mir-103a-1/Downstream/9269000;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/1207359, chr5-CpG: 68/Downstream/2523292

Upstream sequence

GCAGCGGGGAGCGCGCGGCATCGCGGGGGTGGCCGGGGCCAGGGCTTCCCACGTGCGCAGCAGGACGCAGCGCTGCCTGAAACTCGCGCCGCGAGGAGAg

Downstream sequence

ATGAGCACTTTCTTTGTGAACACAGACTTTTGCATTTGTGAATTCAGAATAAATTATGGTCCCCAAATTTCTTCTTTTTTCTTCTTTAATTTCTGCATTC