VISDB Viral Integration Site DataBase

VIS ID

TVIS10014597

Fusion event

HBV-RPP40 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2018

Orient

-

Integrated sequence

ATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCG| |GGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTG

Chromosome

chr6

Cytoband

p25.1

Reference genome

Start

End

5001670/5001436 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-3658 ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-3653-3p ; hsa-mir-6832-3p ; hsa-mir-4511 ; hsa-mir-548b-3p ; hsa-mir-4282 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-3613-3p

Nearest miRNA

hsa-mir-4645/Upstream/2147329; hsa-mir-10398/Downstream/146797;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/224120, chr6-CpG: 41/Downstream/2315

Upstream sequence

gaccagcttggttgtggagaccctaacccagcggcgctagaggacccacacacagaaatatagcatgtggagtaggaaatcaggggactcacagccttca

Downstream sequence

GTTCTTCATATCTTCACTGGAGAGGACACACATGGGGGCTACCACAAGATAAGCATGTGGCCACTGTACAGGTGAGTTATGTAGTGTGGGTGGAATCCCT