VISDB Viral Integration Site DataBase

VIS ID

TVIS10014599

Fusion event

HBV-DPP6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1382

Orient

+

Integrated sequence

CCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTG| |CTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGAC

Chromosome

chr7

Cytoband

q36.2

Reference genome

Start

End

154532587/154740877 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-4668-5p ; hsa-mir-3153 ; hsa-mir-513b-3p ; hsa-mir-1276 ; hsa-mir-497-3p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-511-5p ; hsa-mir-6830-3p

Nearest miRNA

hsa-mir-10399/Upstream/3307238; hsa-mir-153-2/Downstream/2833459;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/435681, chr7-CpG: 22/Downstream/9472

Upstream sequence

tcattcctttaatccttccttcttttcttTTTCTTTTTTTGTTGCTATTTCCTCTTCAGCTTCACTTTCTTTTAGCATGAGTTTAAGATAATTAAATAAA

Downstream sequence

CTATCTGCCCTAAAGGAATCAGTCTTCTGTCTCCTTTACTCCCCATTTTTTTCTTTCTATAAAATTTGCATTATTGGCATAACTTTTCTCTTTACTATGG