C8orf34 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014611
Fusion event
HBV-C8orf34 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|
Start
1849
Orient
+
Integrated sequence
GGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTT| |GTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACT
Host Sequence
Chromosome
chr8
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
69565885/68653650 (Hg38)
End
69565885/68653650 (Hg38)
Orient
+
Location type
Intronic
Target gene
C8orf34
Nearest miRNA
hsa-mir-124-1/Upstream/4274393; hsa-mir-10400/Downstream/5894893;
Nearest TSS
ENST00000518652/Upstream/28191; ENST00000528286/Downstream/199113;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/322082, chr8-CpG: 224/Downstream/1178213
Upstream sequence
TGGGAAGATTTTGTCATTTTCTTTTTGTTTCTGCATTCTGCTGTGAGAGGTTAGTCTTTATGTTGGTTATTACCTTATTTTGGAATAATATTTTGAAATA
Downstream sequence
aaagacagctggatagctctctaaactcttcttgtaggagtactaattgcgttcatgagggatcttccctcatggcctacatacctcccaaaggccccac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate