Basic Information
VIS ID
TVIS10014613
Fusion event
HBV-chr7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1507
Orient
-
Integrated sequence
CGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGGCTCTACCGTCCCCTTCTTCATCTGCCGT| |TCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGC
Host Sequence
Chromosome
chr7
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
52802406/52734712 (Hg38)
End
52802406/52734712 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1183/Upstream/7852912; hsa-mir-10399/Downstream/4221073;
Nearest TSS
ENST00000635602/Upstream/541799; ENST00000408890/Downstream/300930;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/460142, chr7-CpG: 52/Downstream/300870
Upstream sequence
TTATAAAGTAAATAAGCCAGCAGCCTAAAACAATGtaaaatttaaaaaaattttttCAATATTGTAAAATGTTCACACTTGTATACAAACTCATATAGTA
Downstream sequence
ACAGCAAACAAACTAGGTTTTCTTTTTAAGTGCCATCTCCTGGAGAAAGAGGTCAGGCTGAGAAATGCCCTCTATTCTCACTTATCCTTTACAAAATTCA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate