Basic Information
VIS ID
TVIS10014621
Fusion event
HBV-chr9 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
1802
Orient
+
Integrated sequence
ATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGT| |TCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCAT
Host Sequence
Chromosome
chr9
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
24396871/24396873 (Hg38)
End
24396871/24396873 (Hg38)
Orient
-
Fragile sites / regions
FRA9C
Nearest miRNA
hsa-mir-101-2/Upstream/2884688; hsa-let-7a-1/Downstream/4466753;
Nearest TSS
ENST00000422679/Upstream/498819; ENST00000602614/Downstream/148803;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/545349, chr9-CpG: 111/Downstream/1280623
Upstream sequence
tgagaaacttctttgtgaggtgtgcattcaactcacagagttgatcttatcttatcattgagcagttttgaatctctctttttgtagaatctgcaagtgg
Downstream sequence
tgcaggcagtctatcgtgggactttaccttgtgactgtgtgagtcaatcctccttaataaacttcctttcatatatacatatatcctattagttctgtcc
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
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