VISDB Viral Integration Site DataBase

VIS ID

TVIS10014623

Fusion event

HBV-TTLL9 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2734

Orient

-

Integrated sequence

TTATGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGATAAAGGCATTAAACCTTATTATCCTGAACATGCAGTTAATCATTACTTCAA| |AACTAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCTTCATTTTGTGGGTCACCATATTCTTGGGAA

Chromosome

chr20

Cytoband

q11.21

Reference genome

Start

End

30502086/31914283 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-6722-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4533 ; hsa-mir-9500 ; hsa-mir-6888-5p ; hsa-mir-552-3p ; hsa-mir-4428

Nearest miRNA

hsa-mir-103a-2/Upstream/307043; hsa-mir-1-1/Downstream/323512;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/34121, chr20-CpG: 53/Downstream/37437

Upstream sequence

AGAATTTTTCACTGAGACTTTCTAAGAGTCGGGATGCTTTACTCAGTAAATAATAGAAAATCCAAATAACAGTAGCTTAAACAAGAGGGcaagacttctg

Downstream sequence

tactgtttttatgccatgggcctctttgacatctggtgaaatgtgtggaccctatcacagaatagtggtgtttttttaaccacttcattgaaacataatt