VISDB Viral Integration Site DataBase

VIS ID

TVIS10014624

Fusion event

HBV-CXCL3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2935

Orient

-

Integrated sequence

AAGAGCTACAGCATGGGAGGTTGGTCTTCCAAACCTCGACAAGGCATGGGGACGAATCTTTCTGTTCCCAATCCTCTGGGATTTTTTCCCGATCACCAGT| |TGGACCCTGCGTTCGGAGCCAACTCAAACAATCCAGATTGGGACTTCAACCCCAACAAGGATCACTGGCCAGAGGCAAATCAGGTAGGAGCGGGAGCATT

Chromosome

chr4

Cytoband

q13.3

Reference genome

Start

End

74901473/74035756 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-204-5p ; hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-3161 ; hsa-mir-100-3p

Nearest miRNA

hsa-mir-12113/Upstream/7758828; hsa-mir-1243/Downstream/2537812;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/37144, chr4-CpG: 60/Downstream/2480

Nearest cancer related gene

CXCL3(OG, No orient, 0)

Upstream sequence

ctatgcagatgaggaaactgaggcacagagtgacagtttctcaccaggctaggatttgaacccaagtagtctggatccagagcccAATACTGTGCTTTTC

Downstream sequence

agctacacgcacctggagaggggaattaagcttcaccttcgggaaggaggagactatactcatattatcagcaattcttctgtaaagatgtgtctcttct