VISDB Viral Integration Site DataBase

VIS ID

TVIS10014627

Fusion event

HBV-SLC1A7 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

759

Orient

+

Integrated sequence

GTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGG| |GCCAAGTCTGTACAACATCTTGAGTCCCTTTTTACCTCTATTACCAATTTTCTTTTGTCTTTGGGTATACATTTGAACCCTAATAAAACCAAACGTTGGG

Chromosome

chr1

Cytoband

p32.3

Reference genome

Start

End

53589378/53123706 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-647 ; hsa-mir-6762-3p ; hsa-mir-604 ; hsa-mir-4660 ; hsa-mir-6504-5p ; hsa-mir-3064-5p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-4793-5p ; hsa-mir-6736-3p ; hsa-mir-6501-3p

Nearest miRNA

hsa-mir-12136/Upstream/1287304; hsa-mir-101-1/Downstream/930373;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/30736, chr1-CpG: 53/Downstream/72931

Upstream sequence

cagggccagccctccgggcatcgggctgggcctcccagaggagggcacagctggatggagcctcgaaggccaagtaggaattctctaactggaagggagc

Downstream sequence

gagagCATGGAAGTCTGTGGTGCAGGATAAAGCCTGGGAGCTTTTCGGAGTCACCAGGCTGGAGGTCTGACCCCACCCGCAGCCCACAGCGGGCCACGTT