Basic Information
VIS ID
TVIS10014628
Fusion event
HBV-ADAM3A integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
AP011098.1
Start
2484
Orient
-
Integrated sequence
CGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATCCCTTGGACTCATAAGGTGGGAAACTTTA| |CTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTGAGTGGCAAACTCCCTCCTTTCCTAACATTCATTTACAGGAGGACATTATTAATAGATGTCA
Host Sequence
Chromosome
chr8
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
39369790/39512271 (Hg38)
End
39369790/39512271 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADAM3A
Nearest miRNA
hsa-mir-124-1/Upstream/9554923; hsa-mir-10400/Downstream/1758777;
Nearest TSS
ENST00000518652/Upstream/241395; ENST00000520001/Downstream/72218;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/404367, chr8-CpG: 30/Downstream/10435
Upstream sequence
TAACATATGACTTCACATTTGCAAAGTGCTGCCCTTTTTATTAGTATTTTCATTTCACTTTTGAAAACCAAGACAAGTCTGAGAGAAAGTGATCATCTAA
Downstream sequence
TCAATTGAAACTTCTCAGTGTGTCTTAgctccttcagacaccttttttcccctaaaactcctactaatactttcagacatacaaagtttaaatgtccttt
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
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